Thanks for chiming in and sharing ! That PBC itch can be relentless. Some people find a bit of relief with keeping the skin cool (cool showers, cold packs, or sleeping in a cooler room) and using thick, fragrance-free moisturizers right after bathing. I also want to share with you an article from our site that talks more about more treatment options for the itching. You can access it here- https://primarybiliarycholangitis.net/living/itch-treatment. Hope this helps! -Latoya (Team Member)